KMID : 0357220210330030136
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Journal of Korean Society Physical Therapy 2021 Volume.33 No. 3 p.136 ~ p.141
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Dual-Task Training Effect on Cognitive and Body Function, ¥â-amyloid Levels in Alzheimer¡¯s Dementia Patients: A Randomized Controlled Trial
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Nam Seung-Min
Kim Seong-Gil
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Abstract
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Purpose: Dementia is a disease in which cognitive function declines, leading to deterioration of body functions and activities of daily living. The purpose of this study is to explore the effects of dual-task training, including cognitive tasks, on cognitive and body function and ¥â-amyloid levels in Alzheimer¡¯s dementia patients.
Methods: 34 inpatients diagnosed with Alzheimer¡¯s dementia at a nursing hospital located in South Korea. The patients were randomly divided into a dual-task group (n=16) and a single-task group (n=18). Each group was trained for 30 minutes three times a week for eight weeks. The MMSE-K was used to measure the patients¡¯ cognitive function. To assess the patients¡¯ static balance ability, their LOS was measured using BioRescue. while dynamic balance was measured using the BBS. The 10MWT were conducted to evaluate the patients¡¯ walking ability. Blood analysis was performed to measure levels of ¥â-amyloid.
Results: Both groups exhibited statistically significant improvements in gait function after the training (p<0.05). The dual-task group exhibited statistically significant differences in cognitive function, static and dynamic balance function, and ¥â-amyloid levels after training (p<0.05). A significant difference was observed between the two groups (p<0.05).
Conclusion: Dual-task training were found to be effective in improving cognitive and bodily functioning and reducing ¥â-amyloid levels in Alzheimer¡¯s dementia patients. Thus, this may be suggested as an effective exercise method for the treatment and early prevention of Alzheimer¡¯s dementia.
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KEYWORD
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Alzheimer¡¯s disease, Task performance, Cognition, Human activities, Amyloid beta protein, Dementia
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